What Part Of The Brain Controls Thirst Which limbic system regulates thirst and body temperature? Hypothalamus. The hypothalamus regulates a wide variety of behavioral and physiological activities. It regulates many autonomous functions such as hunger, thirst, body temperature and sexual activity. What part of the limbic system also regulates thirst and body temperature? HypothalamusWhat’s in the limbic system besides the above? Primary structures of the limbic system include the amygdala, ...